This verse describes the beginning, the birth of Ayurveda.

Brahma is the creator of everything that exists. This is crucial. What does it mean? A creator can be somebody who creates something separate from themselves, in the modern concept, in the world of dualism (Christians believe that God is separate, for example). The Vedic concept, the original concept, is that there is no difference between the Doer and what is done. That is the non-dualistic concept. The consciousness of the cosmos is not separate from the universe itself, as the physicist Einsten later also declared. In the non-dualistic concept, it is the universe itself that is Brahma/God. Brahma is ageless, eternal and timeless. Other parts of the universe are born, live and then die according to time. In Ayurveda, Brahma is the flow of the universe, and Ayurveda itself is just as old as the universe.   

We can recall the discussion of maya and its 14 levels, that all forms that manifest pass through all those levels in sequence and then repeat in a cyclical fashion, from the unmanifest to the manifest and back again, like water evaporating and then becoming solid and then liquid again. We consider whatever is perceivable to be the "beginning", without understand that whatever we can perceive is actually just a section of the entire process. 

The birth of human beings on the planet is described in the Baghavadgita, verse 4, which describes how Brahma became the sun with its light and how from the light eventually comes the king who dispenses wisdom. This verse lists the succession of the beings through whom this wisdom has been handed down. This is essentially another way of discussing Einstein's famous equation e = mc2, which posits that everything is energy. We are familiar with this concept from the way automobiles function, for example - without a fuel source, nothing moves. Our bodies and our lives function the same way. The energy itself is never born and never dies. Yogis call this Atma, the immortal.     

The assumption is that there is one supreme consciousness which is responsible for managing the universe, from the most subtle forms to a gigantic object. Ayurveda is the project documentation of all animate and inanimate beings and objects in the universe. Ayurveda was passed on from the supreme consciousness to the consciousness of an ordinary human being.

In Indian philosophy, this consciousness is called Brahma. In India, people have been brought up in the knowledge that all things around them, including their soul and body, are part of the universe, belong to the supreme consciousness. In other words, each individual owns nothing, there is nothing which belongs just to the individual. This idea is different from the Western way of thinking.

Indian sages say that this knowledge, Ayurveda, was given to the various gods by the supreme consciousness Brahma and gradually to a sage, Agnivesha and to others, first orally and later in writing.

The Charaka Samhita is the oldest such writing, and after that other writings followed, such as the Sushruta Samhita, which have been expanded as the knowledge of Ayurveda.

The Vagbhatta sage, who lived in the time of Buddhism, thoroughly studied all the ancient writings and gave us a systematic summary of Ayurveda in the form of this Ashtanga Hridayam.